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| Systematic (IUPAC) name | |
| N,N-diethyl-4,4-dithiophen-2-yl-but-3-en-2-amine | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | Schedule I (US) |
| Identifiers | |
| CAS number | 86-14-6  |
| ATC code | None |
| PubChem | CID 6833 |
| DrugBank | DB01533 |
| ChemSpider | 6572  |
| UNII | 2Z91X9052O |
| Chemical data | |
| Formula | C16H21NS2 |
| Mol. mass | 291.477 g/mol |
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| Physical data | |
| Melt. point | 152–153 °C (306–307 °F) |
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Diethylthiambutene (Thiambutene, Themalon, Diethibutin, N,N-Diethyl-1-methyl-3,3-di-2-thienylallylamine) is an opioid analgesic drug developed in the 1950s[1] which was mainly used as an anesthetic in veterinary medicine and continues, along with the other two thiambutenes dimethylthiambutene and ethylmethylthiambutene to be used for this purpose, particularly in Japan.[2][3] It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
References [edit]
- ^ BECKETT AH, CASY AF, HARPER NJ, PHILLIPS PM. Analgesics and their antagonists: some steric and chemical considerations. II. The influence of the basic group on physico-chemical properties and the activity of methadone and thiambutene-type compounds. Journal of Pharmacy and Pharmacology. 1956 Nov;8(11):860-73.
- ^ Hayes MJ. The use of thiambutene hydrochloride. The Veterinary Record. 1968 Nov 16;83(20):528.
- ^ Harbison WD, Slocombe RF, Watts SJ, Stewart GA. Thiambutene and acepromazine as analgesic and preanaesthetic agents in horses and sheep. Australian Veterinary Journal. 1974 Dec;50(12):543-6.
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